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Nizoral Liver Damage Lawsuit
Nizoral (ketoconazole) is an anti-fungal medication was until recently much prescribed for numerous fungal infections, but is now reduced in the United States to use against endemic mycoses fungal conditions, to being a last line of defense when other drugs fail to help, or to use by those who are physically intolerant to all other fungal treatment options. Nizoral works by blocking the production of ergosterol, a necessary element in the cell membranes of fungus cells and thus precluding their survival. It has now been shown, however, to damage the liver, adrenal glands, and heart rhythms of many patients. There are now a multitude of class action and individual law suits against Johnson and Johnson for distributing this drug without adequate warning labels.
The Recent Reactions Against Nizoral
Though Nizoral met with FDA approval in 1981, on July 26, 2013, the FDA reversed course and required new black box warning labels to alert the public to the drug’s potential liver-damaging side effects as well as to its affect on adrenal glands and negative interactions with numerous other drugs on the market. They stopped short of banning the drug, but especially warned against those with prior liver weaknesses using it and effectively demoted it to a last-resort drug in the United States.
The Public Citizen, a consumer watchdog organization, went further and put the Nizoral on its Worst Pills List and suggested it should never be used at all. Over in Europe, the European Medicines Agency (EMA) demanded the drug never be prescribed again and be immediately recalled from pharmacies, hospitals, and all points of sale since the risks in their estimation out-weigh any potential benefits.
Nizoral comes in creams, foams, skin gels, and shampoos, but only the tablet form, which makes up approximately one-eighth of recent prescriptions for this drug, has been found to cause liver and other problems in users. Anyone currently taking this drug, particularly the tablets, should immediately see their doctor to see if they can switch to a different treatment method. Johnson and Johnson, even before the FDA turnabout, had already ceased producing this product but has not yet issued a recall.
Anyone suspecting they have sustained bodily harm from taking this drug should contact legal help as soon as possible to ensure that they receive a full compensation.
Severe Liver Damage Caused by Nizoral Use
A recent Argentina study of Nizoral patients has resulted in doctors in that nation taking immediate and extreme precautions whenever administering the drug due to its potential to cause liver failure. Two deaths from liver toxicity and one case of serious but not yet fatal liver failure were discovered among the study’s patients.
Another study in Britain found that one out of every 500 patients who were prescribed Nizoral and had had no prior liver problems throughout their lives were at high risk of serious liver failure after taking the drug. These studies are a part of the growing recognition that Nizoral is much more dangerous to the liver than other anti-fungal drugs.
Liver damage, called by physicians hepatoxicity, is an incredibly scary condition that can result in the need for a costly transplant or in premature death. Although the harmful effects of Nizoral on the liver are sometimes reversible, in other cases the damage is permanent. One of the most ominous factors involved in the Nizoral liver damage instances is the observation that regardless of how long a patient has been using the drug, whether for a long time in small doses or for a short time in heavy doses, damage to the liver can result.
Since the liver’s filtration of body toxins and other vital functions of the organ are essential to health and even to life, it is imperative to recognize and quickly treat any adverse liver conditions as soon as possible. Some of the signs of liver dysfunction include: a loss of appetite, vomiting, nausea, fever, excessive tiredness, jaundice of the skin or the whites of one’s eyes, overly dark urine, overly light-colored feces, pains or swelling in that part of the abdomen near the liver, constant skin irritation, and easily suffering bruises and bleeding. If you have been on Nizoral and are experiencing some of these symptoms, you should see your doctor and also contact a good injury attorney.
Adrenal Problems Resultant from Nizoral
By lowering the body’s natural levels of corticosteroid production, this drug has potential to cause adrenal insufficiency. This is because the same elements in Nizoral that block fungal ergosterol synthesis also curtail adrenal gland steroid production. This results in an imbalance of the water, salt, and mineral supplies in the body and can cause such side effects as gynecomastia in men and menstrual irregularity in women.
Heart Conditions Stemming from Nizoral
By interacting negatively with a wide range of prescription drugs that were not anticipated nor warned against on Nizoral labeling, life-threatening cardiac side effects can ensue. Some of the drugs that do not “mix well” with Nizoral are: Tikosyn,
Quinidine, Orap, and Propulsid. Irregular heart beat is the main dangerous side effect. One major form is QT interval prolongation which is a specific kind of accelerated heart rate that can be fatal. Cardiac arrest, unnatural heart palpitations, ventricular fibrillation, and other heart rhythm problems that can lead to sudden death can potentially result from Nizoral’s interactions with other drugs.
Getting Legal Help to Pursue Damages
We are an experienced law firm that will work tirelessly to bring just compensation to you for any liver or other damage caused you or a loved one by Nizoral. This was until just recently a very widely prescribed medicine and the quantity of lives affected has thus led to the forming of class action law suits, but individual litigation is also possible, especially in extreme cases which would require greater than average compensation.
Significant levels of financial reimbursement for the pain, injury, medical expenses, and loss of income caused by this poorly labeled and dangerous drug Nizoral are very likely winnable in the near future. If you would gain full and fair compensation for injuries inflicted upon you and help to force pharmaceutical companies to act more conscientiously in the future for the protection of future consumers, then you can count on our dedicated and highly knowledgeable team of lawyers to come to your aid. We have gained much legal wisdom through our years of serving the public by fighting for victims’ rights, and we welcome the opportunity to carry that fight forward in the arena of Nizoral defective product and injury litigation.